Last update
5/1/2025
Research Authors

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Advanced 40+ Acidophilus 1.5 billion CFUproviding:Lactobacillus. acidophilus, (LA-5®)300 million CFULactobacillus rhamnosus GG (LGG®)300 million CFULactobacillus paracasei (L. CASEI 431®)300 million CFU Bifidobacterium lactis (BB-12®)300 million CFUStreptococcus thermophilus, (TH-4®)300 million CFU
2.4 mg
**

Top Medical Research Studies

8
Lactobacillus aids pigs' health
We explored the effects of Lactobacillus acidophilus fermentation products on weanling pigs that were challenged with a harmful strain of bacteria known as enterotoxigenic F4 Escherichia coli (F4-ETEC). To better understand this, we conducted a detailed study involving eighty pigs, which were divided into five groups based on different diets. This included a control diet, as well as diets supplemented with various fermentation products and zinc oxide.

After inoculating the pigs with F4-ETEC to simulate infection, we observed significant changes in the pigs’ fecal microbiome when they were given a combination of Lactobacillus and Saccharomyces products. These changes in the microbiome were previously linked to better growth performance and overall health in young pigs.

Interestingly, the pigs receiving both Lactobacillus acidophilus and Saccharomyces cerevisiae products showed an increase in final live weight. This suggests that using these postbiotics could help manage performance issues associated with ETEC without needing to eliminate the bacteria entirely from the pigs' environment. Therefore, while Lactobacillus acidophilus was not the sole hero in this study, its combined use proved beneficial in combatting the negative effects of this bacterial challenge.
Read More

Most Useful Reviews

9
Restores intestinal microflora
The complex is fantastic! After having Covid, I experienced digestive issues that were difficult to resolve. A doctor recommended an acidophilus complex, and within just one week, I noticed a significant improvement. After completing a full course, my stool returned to normal. I am deeply grateful to iHerb and recommend it to anyone who has had an infection, undergone antibiotic treatment, or those with skin issues. It is truly beneficial for restoring intestinal microflora.
Read More
7.5
Stopped throat infections
1 people found this helpful
In essence, it's amazing; however, the latest batch has a foul odour due to the plastic packaging. I have been using this for a couple of years, and it greatly helps me feel well overall. Since I began using it, I have not had the flu, and my stomach is much more stable. Previously, I suffered from frequent throat infections, but that ceased with this product. I must mention that my most recent order in May 2021 arrived in this new plastic packaging. While I prefer glass as it's healthier, the more pressing issue is that these capsules now have a chemical smell and taste. I'm unsure why this change has occurred.
Read More
7.5
Eczema improvement
Currently, this product appears to aid my eczema due to the bacterial strain L.casei. I am very pleased with the results!
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
  • All Researches
8
Lactobacillus aids pigs' health
We explored the effects of Lactobacillus acidophilus fermentation products on weanling pigs that were challenged with a harmful strain of bacteria known as enterotoxigenic F4 Escherichia coli (F4-ETEC). To better understand this, we conducted a detailed study involving eighty pigs, which were divided into five groups based on different diets. This included a control diet, as well as diets supplemented with various fermentation products and zinc oxide.

After inoculating the pigs with F4-ETEC to simulate infection, we observed significant changes in the pigs’ fecal microbiome when they were given a combination of Lactobacillus and Saccharomyces products. These changes in the microbiome were previously linked to better growth performance and overall health in young pigs.

Interestingly, the pigs receiving both Lactobacillus acidophilus and Saccharomyces cerevisiae products showed an increase in final live weight. This suggests that using these postbiotics could help manage performance issues associated with ETEC without needing to eliminate the bacteria entirely from the pigs' environment. Therefore, while Lactobacillus acidophilus was not the sole hero in this study, its combined use proved beneficial in combatting the negative effects of this bacterial challenge.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Restores intestinal microflora
The complex is fantastic! After having Covid, I experienced digestive issues that were difficult to resolve. A doctor recommended an acidophilus complex, and within just one week, I noticed a significant improvement. After completing a full course, my stool returned to normal. I am deeply grateful to iHerb and recommend it to anyone who has had an infection, undergone antibiotic treatment, or those with skin issues. It is truly beneficial for restoring intestinal microflora.
Read More
7.5
Stopped throat infections
1 people found this helpful
In essence, it's amazing; however, the latest batch has a foul odour due to the plastic packaging. I have been using this for a couple of years, and it greatly helps me feel well overall. Since I began using it, I have not had the flu, and my stomach is much more stable. Previously, I suffered from frequent throat infections, but that ceased with this product. I must mention that my most recent order in May 2021 arrived in this new plastic packaging. While I prefer glass as it's healthier, the more pressing issue is that these capsules now have a chemical smell and taste. I'm unsure why this change has occurred.
Read More
7.5
Eczema improvement
Currently, this product appears to aid my eczema due to the bacterial strain L.casei. I am very pleased with the results!
Read More

Frequently Asked Questions

9
Restores intestinal microflora
The complex is fantastic! After having Covid, I experienced digestive issues that were difficult to resolve. A doctor recommended an acidophilus complex, and within just one week, I noticed a significant improvement. After completing a full course, my stool returned to normal. I am deeply grateful to iHerb and recommend it to anyone who has had an infection, undergone antibiotic treatment, or those with skin issues. It is truly beneficial for restoring intestinal microflora.
7.5
Stopped throat infections
1 people found this helpful
In essence, it's amazing; however, the latest batch has a foul odour due to the plastic packaging. I have been using this for a couple of years, and it greatly helps me feel well overall. Since I began using it, I have not had the flu, and my stomach is much more stable. Previously, I suffered from frequent throat infections, but that ceased with this product. I must mention that my most recent order in May 2021 arrived in this new plastic packaging. While I prefer glass as it's healthier, the more pressing issue is that these capsules now have a chemical smell and taste. I'm unsure why this change has occurred.
7.5
Eczema improvement
Currently, this product appears to aid my eczema due to the bacterial strain L.casei. I am very pleased with the results!
8
Lactobacillus aids pigs' health
We explored the effects of Lactobacillus acidophilus fermentation products on weanling pigs that were challenged with a harmful strain of bacteria known as enterotoxigenic F4 Escherichia coli (F4-ETEC). To better understand this, we conducted a detailed study involving eighty pigs, which were divided into five groups based on different diets. This included a control diet, as well as diets supplemented with various fermentation products and zinc oxide.

After inoculating the pigs with F4-ETEC to simulate infection, we observed significant changes in the pigs’ fecal microbiome when they were given a combination of Lactobacillus and Saccharomyces products. These changes in the microbiome were previously linked to better growth performance and overall health in young pigs.

Interestingly, the pigs receiving both Lactobacillus acidophilus and Saccharomyces cerevisiae products showed an increase in final live weight. This suggests that using these postbiotics could help manage performance issues associated with ETEC without needing to eliminate the bacteria entirely from the pigs' environment. Therefore, while Lactobacillus acidophilus was not the sole hero in this study, its combined use proved beneficial in combatting the negative effects of this bacterial challenge.

References

  1. Cherrington T, Jordan D, Pluske J, Mansfield J, Lugsomya K, et al. Lactobacillus and Saccharomyces fermentation products impact performance and the fecal microbiome in weanling pigs inoculated with enterotoxigenic Escherichia coli. J Anim Sci. 2025;103. 10.1093/jas/skae394
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